Yes, creatine can help with libido. Studies have found that supplementing with creatine monohydrate can increase testosterone levels in both men and women, leading to improved sexual health and performance. In one study, males who took 5g of creatine daily for five weeks experienced a 10% increase in their total testosterone levels, which was linked to an increased sex drive and libido. Women taking 3-5g of creatine per day for eight weeks reported a significant improvement in arousal compared to the control group. Creatine is also believed to improve blood circulation throughout the body by increasing nitric oxide production, which can help enhance physical response during intimate activities.